Preliminary MS laboratories' list in the Romandie Region
(Lake of Geneva Area).

All labs by name based alphabetical order. All labs in Switzerland.
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Biomedical Proteomics Group (BPG) — Geneva Faculty of Medicine

Clinical Chemistry Central Laboratory (LCCC) — HUG

Clinical Proteomics Group (CPG) — Geneva Faculty of Medicine

Contaminants Group — Nestlé Research Center

DiagnoSwiss — Monthey

Drug and Pharmaceutical Analysis Group — University of Geneva

Functional Genomics Group (FUN Gen) — Nestlé Research Centre

Ingredients & Authencity Group — Nestlé Research Centre

Life Sciences Mass Spectrometry Group (LSMS) — University of Geneva

Protein Analysis Facility (PAF) — University of Lausanne

Proteomics Core Facility (PCF) — Geneva Faculty of Medicine

Quantitative Mass Spectrometry Facility (qMSF) — CHUV

Merck Serono Geneva

Service de protection de la consommation (SPCo) - Etat de Genève

SVS MS-plateform — University of Geneva

M-Scan S.A.

Institute of Forensic Medicine Unity of Toxicology

Biomolecular Mass Spectrometry Laboratory (LSMB)

Biomedical Proteomics Group (BPG)
Geneva Faculty of Medicine

Dr Jean-Charles Sanchez
Biomedical Proteomics Research Group (BPRG) - 9052B
Department of Structural Biology and Bioinformatics
University Medical Centre (CMU)
University of Geneva
1 rue Michel Servet
1211 Geneva 4

Equipment (same as for CPG)
1 Q-TOF-MS (Micromass)
1 LCQ XP (Finnigan)
1 MALDI-TOF-MS (Brucker)
2 MALDI-TOF-MS (Applied Biosystems)
2 SELDI-TOF-MS (Ciphergen)
1 MALDI-TOF/TOF-MS (Applied Biosystems)
2 liquid handling robots (home-made)
1 spot picker (ARRM)
2 ELISA robots (Bio-Rad)
1 Fluoroimager and a laser densitometer (Amersham Biosystems)
1-D and 2-D LC and electrophoresis systems
LIMS
Genesis WorkStation 200 (TECAN)

Keywords
proteomics, neurodegenerative diseases, diabetes, cancer, nucleolus, cerebrovascular accident, Alzheimer.

Clinical Chemistry Central Laboratory (LCCC)
Geneva University Hospital (HUG)

Dr Marc Fathi
Hôpitaux Universitaires de Genève
Laboratoire Central de Chimie Clinique (LCCC)
Section de toxicologie
Micheli-Du-Crest 24
1211 Genève 14

Equipment
GC/MS, quad. Agilent 5973
GC/MS, quad. HP 5971
GC/MS, ion trap, GCQ (Finnigan)
LC/MS, quad, MSD (Agilent)
LC/MS, ion trap, Esquire 3000 Plus (Bruker) (being delivered)

Keywords
toxicological screening, drugs therapeutic assays, compounds identification from solids or liquids.

Clinical Proteomics Group (CPG)
Geneva Faculty of Medicine

Prof. Denis F. Hochstrasser and Dr Catherine Zimmermann
Biomedical Proteomics Research Group (BPRG) - 9054
Department of Structural Biology and Bioinformatics
Medical University Centre (CMU)
University of Geneva
1 rue Michel Servet
1211 Geneva 4

Equipment (same as BPG)
1 Q-TOF-MS (Micromass)
1 LCQ XP (Finnigan)
1 MALDI-TOF-MS (Brucker)
2 MALDI-TOF-MS (Applied Biosystems)
2 SELDI-TOF-MS (Ciphergen)
1 MALDI-TOF/TOF-MS (Applied Biosystems)
2 liquid handling robots (home-made)
1 spot picker (ARRM)
2 ELISA robots (Bio-Rad)
1 Fluoroimager and a laser densitometer (Amersham Biosystems)
1-D and 2-D LC and electrophoresis systems
LIMS
Genesis WorkStation 200 (TECAN)

Keywords
proteomics, molecular scanner, gastro-oesophagien cancer, renal diseases, urine.

Contaminants Group
Nestlé Research Center

Dr Philippe Guy
Quality & Safety Assurance Dept.
Nestlé Research Center
Vers-Chez-Les-Blanc
1000 Lausanne 26

Equipment
LC/MS/MS
QuattroLC triple quadrupole (Micromass)
TSQ 7000 triple quadrupole (ThermoFinnigan)
TSQ Quantum Discovery (ThermoFinnigan)
API 3000 triple quadrupole (Applied Biosystems)
4000 QTrap quadrupole/ion trap (Applied Biosystems)
LCQ Deca ion trap (ThermoFinnigan)

GC/MS
Trace GC Ultra & PolarisQ ion trap (Thermofinnigan)
GCQ ion trap (ThermoFinnigan)
HP 6890 (GC) & 5973 MSD (Agilent)

Keywords
foods control (raw materials & finished products), traces analysis, pesticides, veterinary drugs, mycotoxins, vitamins, biomarkers, environmental contaminants, processing contaminants, chemical characterisation & quantification.

DiagnoSwiss
Monthey

Dr Joël S. Rossier and Dr Frédéric Reymond
DiagnoSwiss S.A.
Rte de L'Ile-au-Bois 2
c/o Cimo S.A. - bât. 392
1870 Monthey

Equipment
1 MSD, ion trap (Agilent)
1 capillary LC (Agilent)
1 Spectrum Millenium server (Agilent)
Disposable microchip-based ESI-tips
Off-Gel® electrophoresis pre-fractionation systems
1-D and 2-D electrophoresis systems

Keywords
proteomics, diagnostics, microchips, affinity tests, physicochemical characterisations, protein pre-fractionation, sequencing and identification, service activities.

Drug and Pharmaceutical Analysis Group - LCAP
University of Geneva

Prof. Jean-Luc Veuthey and Dr Serge Rudaz
University of Geneva
Laboratory of Pharmaceutical Analytical Chemistry
20, Bd d'Yvoy
1211 Genève 4

Equipment
HP 1100 MSD, with ESI, APCI and APPI sources
HP 5972 (for GC coupling)
Agilent LC 1100
Agilent cap-LC 1100
Agilent HPCE
GC HP 5890 series II

Keywords
capillary electrophoresis (CE), ESI mass spectrometry, pharmaceutical analysis, biological fluids.

Functional Genomics Group (FUN Gen @ NRC)
Nestlé Research Center

Dr Martin Kussmann
Functional Genomics
Bioanalytical Science Department
Nestlé Research Center
Vers-chez-les-Blancs
1000 Lausanne 26

Equipment
Proteomics
Bruker MALDI-ToF-ToF
Finnigan ion-trap (routine 2D-LC-LC)
Micromass Q-ToF (optional 2D-LC-LC)
Genetix 2DE imager and spot picker
Tecan liquid handler

Genomics
Affymetrix gene expression analysis platform
Hamilton liquid handler

Organic Mass Spectrometry
Waters / Micromass Quattro LC-MS/MS
Finnigan LC/GC/CE-MS/MS
Finnigan GC-MS

Keywords
Technology development
shotgun and gel-based proteomics, quantitative proteomics, MALDI fingerprinting and -imaging of intact cells and bacteria, analysis of protein complexes.

Research applications
digestive health: gut stress markers, gut transporters: integrating proteomics and transcriptomics, obesity: early markers for disposition, allergy: early markers for disposition, milk: bioactive proteins and their complexes, probiotics: membrane- and secreted proteins.

Ingredients & Authencity Group
Nestlé Research Center

Dr Elif Buyukpamukcu
Ingredients and Authencity
Quality and Safety Assurance Department
Nestlé Research Center
PO Box 44
1000 Lausanne 26

Equipment
4000 Q TRAP (linear ion trap, Applied Biosystems | MDS Sciex)
API 4000 (triple quadrupole, Applied Biosystems | MDS Sciex)
MSD (single quadrupole, Agilent)

Keywords
quantitative analysis, vitamins, proteins, peptides, lipids, carbohydrates, polysaccharides, oligosaccharides, prebiotics, plant extracts.
food, pet food, cereals, infant formula, confectionary, ingredients, emulsifiers, authenticity, rwa materials.

Life Sciences Mass Spectrometry Group (LSMS)
University of Geneva

Prof. Gérard Hopfgartner
University of Geneva
Life Sciences Mass Spectrometry
20, Bd d'Yvoy
1211 Genève 4

Equipment
Q STAR XL (Applied Biosystems | MDS Sciex), with ESI, nanospray and o-MALDI sources
4000 Q TRAP (Applied Biosystems | MDS Sciex)

4000 Q TRAP with FlashQuan MALDI Source (FlashQuan)
Q TRAP (Applied Biosystems | MDS Sciex), with ESI and APCI sources
LCMS 2010 A (Shimadzu), with ESI and APCI sources
API III plus (Applied Biosystems | MDS Sciex)
Prospekt 2 (Spark Holland), with mono- and dual-HPD, and TASPE
NanoMate 400, NanoFact (Advion BioSciences)
LC-10 HPLC systems (Shimadzu), with SIL-HT

Keywords
pharmacokinetics, metabolism, proteomics, C. elegans, micro-chips MS, CID fragmentation, high-throughput analysis, metabolomics.

Protein Analysis Facility (PAF)
University of Lausanne

Dr Manfredo Quadroni, Head, Protein Analysis Facility
University of Lausanne, Switzerland
c/o Departement de Biochimie,
Ch. des Boveresses 155,
1066 EPALINGES

Equipment
Q STAR Pulsar i qqTOF (Applied Biosystems | MDS Sciex), with electrospray and MALDI sources
QTRAP 2000 triple quadrupole-linear ion trap (Applied Biosystems | MDS Sciex), with electrospray source
2 nano-capillary HPLC systems (DIONEX-LC Packings).
access to a Voyager RP MALDI-TOF (ABI), property of Biochemistry

Activities
Core facility for academics and the private sector. Projetcts based on collaborations.

Keywords
proteomics, protein identification, tandem mass spectrometry, complex
protein mixtures, capillary liquid chromatography, peptide sequencing, post-translational modifications, core facility, service activity, 1D electrophoresis, 2D-electrophoresis.

Proteomics Core Facility (PCF)
Geneva Faculty of Medicine

Dr Jean-Charles Sanchez, Patrizia Arboit and Dr Carla Pasquarello
Proteomics Core Facility (1st floor)
Centre Médical Universitaire (CMU)
1, rue Michel-Servet
1211 Genève 14

Equipment
1 LCQ XP (Finnigan)
1 MALDI-TOF-MS (Brucker)
1-D and 2-D LC and electrophoresis systems (Bio-Rad)
LIMS (Applied Biosystems)
1 fluoroimager and a laser densitometer (Amersham Biosystems)

Keywords
service, mass spectrometry, two-dimensional gel electrophoresis, identification, PTMs.

Quantitative Mass Spectrometry Facility (qMSF)
Lausanne University Hospital (CHUV)

Dr Bertrand Rochat
Quantitative Mass Spectrometry Facility
Département de Recherche
CHUV - BH18, 218
1001 Lausanne

Equipment
TSQ Quantum triple quadrupole MS (Thermofinnigan)
LTQ Linear Trap MS (Thermofinnigan)

Activities
qMSF is a platform of mass spectrometer instruments of the Research Department at CHUV in Lausanne. The platform is open to anyone who needs this technology for biomedical, clinical, applied research and diagnostic applications. The Project Leader in charge of the platform is Dr Bertrand Rochat.

Keywords
biomedical, clinical, applied research, diagnostic, drug quantitation, drug metabolism, phenotyping, pharmacokinetics, glycoproteins.

Merck Serono Geneva

Francis Vilbois
Merck Serono International SA
9, chemin des Mines
1202 Geneva, Switzerland

Equipment
Q-TOF 1 from Micromass, equipped with nanospray ion source
Q-STAR Ultima from Sciex, equipped with nanospray and MALDI sources
Voyager DE-PRO MALDI-TOF from ABI
Ciphergen ProteinChip Biomarker System
Ultimate Nano-LC system from Dionex
ProTeam robot from TECAN
HP 1100 HPLC system
ABI 494 Procise Protein Sequencer
HP 1090 Amino Acid Analyser

Keywords
analytical protein chemistry, proteomics, protein sequencing, MS, MS/MS, protein biomarkers, QC of recombinant proteins, discovery of novel protein
therapeutics or targets.

Service de protection de la consommation - SPCo
Direction générale de la santé

Dr Patrick Edder and Dr Didier Ortelli
Service de protection de la consommation
22, quai Ernest-Ansermet
case postale 76
1211 Genève 4 Plainpalais

Equipment
LC/MSMS, QuattroMicro triple quadrupole (Micromass) and LC HP1100 (Agilent)
GC/MS, PolarisQ ion trap and GC TraceGC 2000 (Thermofinnigan)
GC/MS, Saturn4D ion trap and GC Star3400 (Varian)
GC/MS, 5973 quadrupole and GC 6890 (Agilent)
GC/MS, 5971 quadrupole and GC 5890 (Agilent)

Keywords
foods control, residues analysis, pesticides, veterinary drugs, vitamins, aroma, cosmetics

SVS MS-plateform
(Science, Vie & Société)

Prof. Gérard Hopfgartner and Dr Emmanuel Varesio
University of Geneva
Laboratory of Pharmaceutical Analytical Chemistry
SVS MS Plateform
20, Bd d'Yvoy
1211 Genève 4

Equipment
Axima-CFR+ (MALDI-TOF MS, Kratos Analytical)
Esquire 3000 (ion trap MS, Brucker Daltonics)
Alliance HT 2790 (HPLC system, Waters)
Xcise (Shimadzu Biotech and Proteome Systems)

Keywords
MS-plateform, SVS, proteins and peptides MS analysis, Low molecular weight compounds, MALDI, micro-LC-MSn.

M-Scan S.A.

Dr. Luc-Alain Savoy
M-Scan S.A.
12, Chemin des Aulx
1228 Plan-les-Ouates

Equipment 
Q-TOF MICRO (Micromass | Waters), with ESI and nanospray coupled with an Alliance HT 2795 (HPLC system, Waters)
QUATTRO PREMIER XE (Micromass | Waters) with ESI and APCI coupled with an Acquity UPLC (Ultraperformance LC system, Waters)
API3000 triple quadrupole (Applied Biosystems | MDS Sciex) with TurboIon Spay (ESI) and APCI Heated Nebulizer coupled with an HP 1100 (HPLC system, Agilent).

Keywords
mass spectrometry service, qualitative analysis, quantitative analysis, pharmaceutical analysis, bioanalysis, pharmacokinetics, high-throughput analysis, proteomics, protein sequencing, glycoprotein, metabolism.

Institute of Forensic Medicine
          Unity of Toxicology

Dr Christian Staub
Institut Universitaire de Médecine Légale
Unité de Toxicologie
9 avenue de Champel
1211 Genève 4

Equipment
GC/MS, quadrupole, HP 5988
GC/MS, quadrupole, HP 5972
GC/MS, quadrupole, Agilent 5973
LC/MS, MSD, Agilent 1100
GC/MS, ion trap, Varian 2000
GC/MS/MS, triple quadrupole, Varian 1200

Keywords
Forensic Toxicology, Postmortem Toxicology, Hair Analysis,
Analysis of Biological Fluids, Drugs Screening.

Biomolecular Mass Spectrometry Laboratory (LSMB)

Prof. Yury O. Tsybin
Biomolecular Mass Spectrometry Laboratory
EPFL-FSB-ISIC LSMB, BCH 4312
CH-1015 Lausanne

Equipment

12 T LTQ FT-ICR MS (Thermo)
4.7 T MALDI FT-ICR MS (Varian)
UPLC/HPLC (Thermo)
TriVersa Nanomate (Advion)
Ion sources (ESI, nanoESI, APPI, APCI)
Ion mobility (FAIMS, Thermo)

Keywords
Metabolomics; proteomics; peptide structure; protein structure; post-translational modifications; liquid chromatography; tandem mass spectrometry, FTMS; ECD; ETD; IRMPD; bioinformatics

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webmaster | Burr Loïc | updated : November 2nd, 2007